在MyBatis中配置Druid多數據源主要需要進行以下步驟：

1. 首先，在pom.xml文件中添加Druid和MyBatis的依賴：

<dependency>
    <groupId>com.alibaba</groupId>
    <artifactId>druid</artifactId>
    <version>1.1.23</version>
</dependency>

<dependency>
    <groupId>org.mybatis</groupId>
    <artifactId>mybatis</artifactId>
    <version>3.5.6</version>
</dependency>

2. 然后在application.properties或者application.yml文件中配置Druid的數據源信息，例如：

spring.datasource.druid.datasource1.url=jdbc:mysql://localhost:3306/test1
spring.datasource.druid.datasource1.username=root
spring.datasource.druid.datasource1.password=root

spring.datasource.druid.datasource2.url=jdbc:mysql://localhost:3306/test2
spring.datasource.druid.datasource2.username=root
spring.datasource.druid.datasource2.password=root

3. 創建DruidDataSource配置類，用于配置Druid數據源：

@Configuration
public class DruidDataSourceConfig {

    @Bean(name = "dataSource1")
    @ConfigurationProperties(prefix = "spring.datasource.druid.datasource1")
    public DataSource dataSource1() {
        return DruidDataSourceBuilder.create().build();
    }

    @Bean(name = "dataSource2")
    @ConfigurationProperties(prefix = "spring.datasource.druid.datasource2")
    public DataSource dataSource2() {
        return DruidDataSourceBuilder.create().build();
    }

    @Bean
    @Primary
    public DynamicDataSource dataSource(@Qualifier("dataSource1") DataSource dataSource1, @Qualifier("dataSource2") DataSource dataSource2) {
        Map<Object, Object> targetDataSources = new HashMap<>();
        targetDataSources.put("dataSource1", dataSource1);
        targetDataSources.put("dataSource2", dataSource2);

        DynamicDataSource dynamicDataSource = new DynamicDataSource();
        dynamicDataSource.setTargetDataSources(targetDataSources);
        dynamicDataSource.setDefaultTargetDataSource(dataSource1);

        return dynamicDataSource;
    }

    @Bean
    public SqlSessionFactory sqlSessionFactory(@Qualifier("dataSource") DataSource dataSource) throws Exception {
        SqlSessionFactoryBean sqlSessionFactoryBean = new SqlSessionFactoryBean();
        sqlSessionFactoryBean.setDataSource(dataSource);
        return sqlSessionFactoryBean.getObject();
    }

    @Bean
    public SqlSessionTemplate sqlSessionTemplate(SqlSessionFactory sqlSessionFactory) {
        return new SqlSessionTemplate(sqlSessionFactory);
    }
}

4. 創建DynamicDataSource類，用于動態切換數據源：

public class DynamicDataSource extends AbstractRoutingDataSource {

    @Override
    protected Object determineCurrentLookupKey() {
        return DataSourceContextHolder.getDataSource();
    }
}

5. 創建DataSourceContextHolder類，用于設置數據源的key：

public class DataSourceContextHolder {

    private static final ThreadLocal<String> contextHolder = new ThreadLocal<>();

    public static void setDataSource(String key) {
        contextHolder.set(key);
    }

    public static String getDataSource() {
        return contextHolder.get();
    }

    public static void clearDataSource() {
        contextHolder.remove();
    }
}

通過以上步驟，就可以實現在MyBatis中配置Druid多數據源。在需要切換數據源的地方，可以通過調用DataSourceContextHolder.setDataSource("dataSource2")來切換到相應的數據源。